RAZ YIRMIYA

1. Cytokines and depression

Yirmiya, R., Endotoxin produces a depressive-like episode in rats. Brain Research, 711: 163-174, 1996. [Abstract]

Yirmiya, R., Behavioral and psychological effects of immune activation: implications for ‘depression due to a general medical condition’. Current Opinion in Psychiatry. 10: 470-476, 1997.

Dantzer, R., Wollman, E. E., Vitkovik, L., and Yirmiya, R., Cytokines and depression: Fortuitous or causative association. Molecular Psychiatry, 4:328-332, 1999. [Abstract]

Dantzer, R., Wollman, E. E., and Yirmiya, R. (Eds.), Cytokines, Stress and Depression. Kluwer Academic/Plenum Press: New York, 1999.

Dantzer, R., Wollman, E. E., Vitkovik, L., and Yirmiya, R., Cytokines, stress and depression: Conclusions and perspectives. In : Dantzer, R., Wollman, E. E., and Yirmiya, R. (eds.), Cytokines, Stress and Depression (Advances in Experimental Medicine and Biology, vol. 461), Kluwer Academic/Plenum Press, New York, 1999, pp. 317-329.

Yirmiya, R., Weidenfeld, J., Pollak, Y., Morag, M., Morag, A., Avitsur, R., Barak, O., Reichenberg, A., Cohen, E., Shavit, Y., and Ovadia, H., Cytokines, ‘depression due to a general medical condition’ and antidepressants drugs. In: Dantzer, R., Wollman, E. E., and Yirmiya, R. (Eds.), Cytokines, Stress and Depression (Advances in Experimental Medicine and Biology, vol. 461), Kluwer Academic/Plenum Press, New York, 1999, pp. 283-316.

Yirmiya, R., Depression in medical illness: The role of the immune system. Western Journal of Medicine, 173: 333-336, 2000.

Yirmiya, R., Pollak, Y., Morag, M., Reichenberg, A., Barak, O., Avitsur, R., Shavit, Y., Ovadia, H., Weidenfeld, J., Morag, A., Newman, M. E. and Pollmдcher, T., Illness, Cytokines and Depression. Annals of the New York Academy of Sciences, 917: 478-487, 2000. [Abstract]

Yirmiya, R., Pollak, Y., Barak, O., Avitsur, R., Ovadia, H., Bette, M., Weihe, E., and Weidenfeld, J., Effects of antidepressant drugs on the behavioral and physiological responses to lipopolysaccharide (LPS) in rodents. Neuropsychopharmacology, 24: 531-544, 2001. [Abstract]

Castanon, N., Leonard, B. E., Neveu, P. J., and Yirmiya, R. Effects of antidepressants on cytokine production and actions. Brain, Behavior and Immunity, 16: 569-574, 2002. [Abstract]

Dantzer, D., Wollman, E. E., and Yirmiya R. Cytokines and depression: An update. Brain, Behavior and Immunity, 16: 501-502, 2002.

Pollak, Y., Orion, E., Ovadia, H. and Yirmiya, R. Experimental autoimmune encephalomyelitis-associated behavioral syndrome as a model of ‘depression due to multiple sclerosis’. Brain, Behavior and Immunity, 16: 533-543, 2002. [Abstract]

Pollak, Y., and Yirmiya, R. Cytokine-induced changes in mood and behavior: Implications for “depression due to a general medical condition“, immunotherapy and antidepressive treatment. International Journal of Neuropsychopharmacology, 5: 389-399, 2002. [Abstract]

Goldstein, I., Levy, T., Galili, D., Ovadia, H., Yirmiya, R., Rosen, H., Lichtstein, D. Involvement of Na(+), K(+)-ATPase and Endogenous Digitalis-Like Compounds in Depressive Disorders. Biological Psychiatry, 60(5):491-499, 2006 [Abstract]

Goshen, I., Kreisel T, Ben-Menachem-Zidon O, Weidenfeld, J., Ben-Hur T. and Yirmiya R. Brain interleukin-1 mediates chronic stress-induced depression in mice via adrenocortical activation and hippocampal neurogenesis suppression. Mol. Psychiatry, 13: 717-728, 2008.

Bilbo, S.D., Yirmiya, R., Amat, J., Paul, E.D., Watkins, L.R., Maier, S.F. Bacterial infection early in life protects against stressor-induced depressive-like symptoms in adult rats. Psychoneuroendocrinology, 33(3):261-269, 2008.

Dantzer, R., Capuron, L., Irwin, M. R., Miller, A. H., Ollat, H., Perry, V.H, Rousey, S., Yirmiya, R. Identification and treatment of symptoms associated with inflammation in medically ill patients. Psychoneuroendocrinology, 33:18-29, 2008.

Shapira-Lichter, I., Beilin, B, Ofek, K., Bessler, H., Ballas, M., Shavit, Y., Seror, D., Grinevich, G., Posner, E., Reichenberg, A., Soreq, H., Yirmiya, R. Cytokines and cholinergic signals co-modulate surgery stress-induced changes in mood and memory. Brain, Behavior, and Immunity, 22(3):388-398, 2008.

Goshen, I., Yirmiya, R. Interleukin-1 (IL-1): A central regulator of stress responses. Frontiers in Neuroendocrinology, 30(1):30-45, 2009.

Maes, M., Yirmyia, R., Noraberg, J., Brene, S., Hibbeln, J., Perini, G., Kubera, M., Bob, P., Lerer, B., Maj, M. The inflammatory & neurodegenerative (I&ND) hypothesis of depression: leads for future research and new drug developments in depression. Metabolic Brain Diseases. 24(1):27-53, 2009.

Yirmiya, R. The inflammatory nature of depression. Frontiers in Neuroscience. 3: 262, 2009.

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