David M. Zucker
|
Department of Statistics |
Last
revised: 11 June 2009 (partial update)
Home Page Map
Born 1961, Baltimore, Maryland, USA.
Moved to Jerusalem, Israel, in September 1992.
One of the best decisions in my life.
Married to Janis Zucker, with six children:
Yossi, Avi, Naomi, Shlomo, Peninah, and Miriam
(all of whom are very nice, if I may say so myself).
Family Picture
Education
JD, 1987, University of Maryland at Baltimore
PhD, 1986, Johns Hopkins University, Mathematical Sciences
(concentration in probability and statistics)
MA, 1981, Johns Hopkins University, Mathematical Sciences
BA, 1980, Johns Hopkins University, Mathematical Sciences
Professional Employment Background
1992-Present Faculty Member
Senior Lecturer - October 1992 to March 2002
Associate Professor - March 2002 to December 2007
Professor - December 2007 to present
Department of Statistics
Hebrew University of Jerusalem
1986-1992 Mathematical Statistician
Biostatistics Research Branch
National Heart, Lung, and Blood Institute (NHLBI)
National Institutes of Health (NIH), USA
1983-1986 Mathematical Statistician
Statistical Evaluation and Research Branch (SERB)
Center for Drugs and Biologics (CDER)
Food and Drug Adminstration (FDA), USA
At the FDA, I was a statistical reviewer of clinical trials submitted in New Drug Applications (NDA's) by drug companies to obtain new drug approvals. At the NIH, I worked mainly on design of large scale NIH-run clinical trials, mostly in the cardiovascular area. I also engaged in various other statistical consulting activities with NIH researchers and in biostatistical methodology research. At the Hebrew University, I have been teaching general statistics and biostatistics courses (at the BA and MA levels) and have been engaged in statistical methods research. I have been the coordinator of the Statistics Departments MA track in biostatistics. Click here to access a Hebrew document describing this program.
In addition to the foregoing full time positions, I have engaged in part-time statistical consulting over the years for a variety of clients, including Hebrew University researchers (especially in the School of Public Health), Teva Pharmaceuticals, Agis Pharmaceuticals, Keryx Biopharmaceuticals, and Neurotrax, Inc.
Research Interests
Survival Analysis
Analysis of Repeated Measurement Data (Continuous and Binary)
Clinical Trial Design, including interim sample size updating
Higher Order Asymptotics
Nonlinear Statistical Models with Covariate Measurement Error
Editorial Service
Co-Editor, Biometrics (term runs from January 2008 to December 2010)
Biometrics websites: (1) IBS, (2) Blackwell Publishing
Associate Editor, Biometrics, 2003-07
Associate Editor, Controlled Clinical Trials, 1998-99
Referee for a variety of statistical and biomedical research journals
Inference for the Proportional Hazards Model with Misclassified Discrete-Valued Covariates, with D. Spiegelman, Biometrics 60:324-334 (June 2004).
In referencing this paper, please cite the published version.
Fortran software for the method:
Documentation
Basic program: (1) Driver, (2) Subroutines
Extended program to cover left truncation: (1) Driver, (2) Subroutines
A
pseudo partial likelihood method for semi-parametric survival
regression with covariate errors.
In
referencing this paper, please cite the published version.
Journal
of the American
Statistical
Association 100:1264-1277
(December 2005).
Selected Recent
Statistical/Scientific Publications
Tian, L, Zucker, DM, and Wei, LJ. (2005). On the Cox model with time-varying regression coefficients. Journal of the American Statistical Association 100:172-183.
Zucker, DM. (2005). A pseudo partial likelihood method for semi-parametric survival regression with covariate errors. Journal of the American Statistical Association 100:1264-1277.
Rosen L, Manor O, Engelhard D, Brody D, Rosen B, Peleg H, Meir M, Zucker D. (2006) Can a handwashing intervention make a difference? Results from a randomized controlled trial in Jerusalem preschools. Preventive Medicine 42:27-32.
Zucker, DM, and Yang, S. (2006). Inference for a family of survival models encompassing the proportional hazards and proportional odds models. Statistics in Medicine 25: 995-1014.
Rosen, L, Manor, O, Engelhard, D, Zucker, D. (2006). In defense of the randomized controlled trial for health promotion research. American Journal of Public Health 96:1181-1186.
Gorfine M, Zucker DM. and Hsu L. (2006). Prospective survival analysis with a general semiparametric shared frailty model: a pseudo full likelihood approach. Biometrika 93:735-741.
Rosen LR, Manor O, Englehard D, Zucker D. (2006). Design of the Jerusalem Handwashing Study: meeting the challenges of a preschool-based public health intervention trial. Clinical Trials 3:376-384.
Zucker DM, Gorfine M, Hsu L. (2008). Pseudo full likelihood estimation for prospective survival analysis with a general semiparametric shared frailty model: asymptotic theory. Journal of Statistical Planning and Inference 138:1998-2016
Zucker DM, and Spiegelman, D. (2008). Corrected score estimation in the proportional hazards model with misclassified discrete covariates. Statistics in Medicine 27:1911-1933. Previous technical report version covering the case of general relative risk functions.
Gorfine M, Zucker DM, Hsu L. (2009). Case-control survival analysis with a general semiparametric shared frailty model: a pseudo full likelihood approach. Annals of Statistics 37:1489-1517.
Rosen LJ, Manor O, Brody D, Englehard D, Shtarkshall R, Zucker D (2009). From pills to programs: lessons from medicine for developing effective lifestyle interventions. Preventive Medicine, in press (DOI:10.1016/j.ypmed.2009.03.010).
Chen YH, and Zucker DM (2009). Case-cohort analysis with semiparametric transformation models. To appear in Journal of Statistical Planning and Inference.
Complete publications list:
click
here
Sample
Size Redetermination for Repeated Measures Studies (see Zucker and
Denne, 2002, Biometrics)
Software
for inflation factor - Nonparametric Approach A
Software
for Nonparametric Approach B (basic method + inflation factor)
Software
for Parametric Approach C (Weibull) (basic method + inflation factor)
Remark
on inflation factor
Inference for a family of survival models encompassing the proportional hazards and proportional odds models
(see Zucker and Yang, 2006, Statistics in Medicine)
Fortran software for the method:
Basic program: (1) Driver, (2) Subroutines
Corrected score estimation in the proportional hazards model with misclassified discrete covariates
(see Zucker and Spiegelman, 2008, Statistics in Medicine)
Fortran software for the method:
Documentation
Code
Alternate version of code without calls to IMSL routines
Sample Driver File
Executable File for Running on PC
Courses Taught (selected list)
Introductory Statistics for Economics Majors B (1st year BA)
Nonparametric Statistics for Nonstatisticians
Statistical Inference and Its Applications A (2nd year BA)
Statistical Inference and Its Applications B (2nd year BA)
Regression and Linear Models (2nd year BA)
Sampling Theory (2nd year BA)
Statistical Models and Their Applications (3rd year BA)
Principles of Research Design and Sampling Theory (2nd/3rd year BA and MA)
Survival Analysis (3rd year BA and MA)
Binary Data Analysis (3rd year BA and MA)
Topics in Biostatistics (3rd year BA and MA)
Measurement Error Models (3rd year BA and MA)
Advanced SAS Applications (3rd year BA and MA)
Repeated Measures Analysis (MA)
Matrix Theory With Statistical Applications (MA)
Asymptotic Statistical Theory (MA and PhD)
Course Materials
Survival Analysis Course Materials
Biostatistics Course Materials
Design Course Materials
Biostatistics Topics Course Materials
Binary Data Analysis Course Materials
Regression Course Materials
Asymptotic Statistics Course Materials
Eastern
Mediterranean Region of the International Biometric Society (EMR-IBS)
In 2001,
the Eastern Mediterranean Region of the International Biometric
Society (EMR-IBS) was founded to foster interaction among
biostatisticians in the Eastern Mediterranean Region. I have served
the EMR in various capacities over the years. In particular, I was,
along with Orly Manor, one of the lead co-organizers of the Fourth
Meeting of the EMR-IBS, held at the Hilton Hotel, Eilat, Israel, on
January 23-25, 2007. I am glad to say that this conference was very
successful. I also served as President of the EMR from May 2007 to May
2009. Link to EMR-IBS regional website
Zucker, D. M. (2004, 2007) (English translation). Voice of Weepers: Commentary of the Dubner Maggid on the Book of Lamentations. Feldheim Publishers, Monsey NY and Jerusalem.
Zucker, D. M. (2005) (English translation). Voice of Rejoicing and Salvation: Commentary of the Dubner Maggid on the Book of Esther. Feldheim Publishers, Monsey NY and Jerusalem.
Zucker, D. M. (2006) (English translation). Voice of the Dove: Commentary of the Dubner Maggid on the Book of Ruth and Chapter 19 of Exodus. Feldheim Publishers, Monsey NY and Jerusalem.
Zucker, D. M. (2008) (English translation). A Voice Shall Sing Forth: Commentary of the Dubner Maggid on the Song of Songs. Feldheim Publishers, Monsey NY and Jerusalem.
Zucker, D. M. (English translation, in preparation). Voice of Nobles: Commentary of the Dubner Maggid on the Book of Ecclesiastes.
The above works were originally published in Hebrew in 1819 posthumously by Rabbi Jacob Kranz, the Maggid of Dubno, under the titles Kol Bochim, Kol Rinah V’Yeshuah, Kol HaTor, Kol Yeshorer, and Kol Negidim, respectively, in a volume called Kol Yaacov containing commentaries on the Five Scrolls. The material was arranged and edited under the direction of Rabbi Kranz’s son Isaac. (In Voice of the Dove, the material on Exodus comes from Ohel Yaacov, the Maggid’s commentary on the Chumash [Five Books of Moses], as compiled by Rav Avraham Dov Beirush Flamm.)
For more information on these works, see www.jlm-dubno-maggid.org.